Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097598 | 0.88 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPTHPGDOPRK1 | |
| SCHEMBL8090064 | 0.87 | GUSB (0.43) | ALDH1A1TSHRMAPTHPGDHTT | |
| SCHEMBL8098673 | 0.87 | ALDH1A1 (0.54) | ALDH1A1TSHRMAPTHPGDHTT | |
| SCHEMBL8098463 | 0.87 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPTHPGDNTMT1 | |
| SCHEMBL8097385 | 0.87 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPTHPGD | |
| SCHEMBL8096918 | 0.87 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPTHPGDNPC1 | |
| SCHEMBL8103590 | 0.86 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPTHPGDCYP2C19 | |
| SCHEMBL8105972 | 0.86 | ALDH1A1 (0.36) | ALDH1A1TSHRMAPTHPGD | |
| SCHEMBL8097455 | 0.86 | ALDH1A1 (0.40) | ALDH1A1TSHRMAPTHPGDNPC1 | |
| SCHEMBL8097010 | 0.86 | HPGD (0.37) | ALDH1A1TSHRMAPTHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |