Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103590 | 0.89 | ALDH1A1 (0.38) | ALDH1A1HPGDCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8097587 | 0.89 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDGAATSHR | |
| SCHEMBL8097598 | 0.87 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL8098680 | 0.86 | LMNA (0.38) | ALDH1A1HPGDCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8096918 | 0.86 | ALDH1A1 (0.38) | ALDH1A1HPGDTSHRMAPTNPSR1 | |
| SCHEMBL8099152 | 0.86 | ALDH1A1 (0.38) | ALDH1A1HPGDCYP2C19TSHRMAPT | |
| SCHEMBL8098673 | 0.86 | ALDH1A1 (0.54) | ALDH1A1HPGDGAACYP2C19TSHR | |
| SCHEMBL8097385 | 0.86 | ALDH1A1 (0.38) | ALDH1A1HPGDTSHRMAPT | |
| SCHEMBL8098463 | 0.86 | ALDH1A1 (0.38) | ALDH1A1HPGDDDB1CRBNTSHR | |
| SCHEMBL8097010 | 0.85 | HPGD (0.37) | ALDH1A1HPGDCYP1A2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |