Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PPIA | P62937 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8100691 | 0.84 | PTGS1 (0.58) | LMNAMAPK1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL8480176 | 0.83 | PTGS1 (0.60) | LMNAGAAPTGS1PTGS2ALDH1A1 | |
| SCHEMBL8092102 | 0.83 | PTGS1 (0.60) | LMNAGAAPTGS1PTGS2ALDH1A1 | |
| SCHEMBL8481953 | 0.82 | PTGS1 (0.59) | PGRLMNAHPGDPTGS1PTGS2 | |
| SCHEMBL8091464 | 0.81 | PTGS2 (0.62) | PGRLMNAMAPK1HPGDPTGS1 | |
| SCHEMBL8104909 | 0.81 | PTGS1 (0.64) | LMNAGAAPTGS1PTGS2ALDH1A1 | |
| SCHEMBL8091401 | 0.81 | PTGS1 (0.60) | LMNAGAAPTGS1PTGS2ALDH1A1 | |
| SCHEMBL8476800 | 0.81 | PTGS1 (0.57) | LMNAGAAMAPK1HPGDPTGS1 | |
| SCHEMBL8101589 | 0.80 | PTGS2 (0.61) | PGRLMNAHPGDPTGS1PTGS2 | |
| SCHEMBL8107162 | 0.80 | PTGS1 (0.61) | PGRLMNAHPGDPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848703-B1 | DERIVATIVES OF BENZOSULPHONAMIDES AS INHIBITORS OF THE ENZYME CYCLO-OXYGENASE II | NYCOMED AUSTRIA GMBH (AT) | 2000-09-27 | — | — | EP | disclosed |