Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3800885 | 0.89 | DPP4 (0.44) | DPP4SPHK2SPHK1ELOVL6GAA | |
| SCHEMBL8101422 | 0.86 | DPP4 (0.45) | DPP4SPHK2SPHK1ELOVL6GAA | |
| SCHEMBL3741039 | 0.79 | CMA1 (0.44) | DPP4ELOVL6ELANE | |
| SCHEMBL13078816 | 0.78 | ELOVL6 (0.40) | DPP4ELOVL6GAATDP1RAB9A | |
| SCHEMBL3747942 | 0.78 | KLK5 (0.44) | DPP4ELOVL6GAATDP1ELANE | |
| SCHEMBL3802747 | 0.76 | DPP4 (0.52) | DPP4ELOVL6FAPDPP8DPP9 | |
| Trifluoroacetic Acid SCHEMBL3742689 | 0.75 | DPP4 (0.46) | DPP4SPHK2SPHK1ELOVL6GAA | |
| SCHEMBL3744756 | 0.74 | ELOVL6 (0.40) | DPP4ELOVL6GAATDP1FAP | |
| SCHEMBL13045313 | 0.74 | PEPD (0.46) | DPP4SPHK2SPHK1ELOVL6GAA | |
| SCHEMBL3749600 | 0.74 | ELOVL6 (0.39) | DPP4SPHK2SPHK1ELOVL6GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037719-A1 | NOVEL COMPOUNDS AS DIPEPTIDYL PEPTIDASE IV (DPP IV) INHIBITORS | LUPIN LIMITED (IN) | 2009-03-26 | — | — | WO | disclosed |