Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 10/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3800885 | 0.97 | DPP4 (0.44) | DPP4SPHK2SPHK1ELOVL6CMA1 | |
| SCHEMBL3741039 | 0.92 | CMA1 (0.44) | DPP4ELOVL6CMA1ALDH1A1PPARG | |
| SCHEMBL3747942 | 0.92 | KLK5 (0.44) | DPP4ELOVL6CMA1GAATDP1 | |
| SCHEMBL3744756 | 0.88 | ELOVL6 (0.40) | DPP4ELOVL6GAATDP1KDM4E | |
| SCHEMBL3749600 | 0.87 | ELOVL6 (0.39) | DPP4SPHK2SPHK1ELOVL6GAA | |
| SCHEMBL3749602 | 0.87 | DPP4 (0.53) | DPP4ELOVL6 | |
| SCHEMBL8099472 | 0.86 | DPP4 (0.43) | DPP4SPHK2SPHK1ELOVL6GAA | |
| SCHEMBL3742876 | 0.85 | ELOVL6 (0.39) | DPP4ELOVL6GAATDP1KDM4E | |
| SCHEMBL8091388 | 0.85 | ELOVL6 (0.39) | DPP4SPHK2SPHK1ELOVL6CMA1 | |
| SCHEMBL3802747 | 0.84 | DPP4 (0.52) | DPP4ELOVL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037719-A1 | NOVEL COMPOUNDS AS DIPEPTIDYL PEPTIDASE IV (DPP IV) INHIBITORS | LUPIN LIMITED (IN) | 2009-03-26 | — | — | WO | disclosed |