Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.35 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098966 | 0.86 | ADRB1 (0.36) | — | |
| SCHEMBL8105384 | 0.85 | PLK1 (0.35) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL8099139 | 0.79 | MAPT (0.36) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL8099041 | 0.77 | MCHR1 (0.38) | ALDH1A1TSHRMAPTTMPRSS4 | |
| SCHEMBL6509757 | 0.76 | MEN1 (0.43) | ALDH1A1MEN1KMT2APHOSPHO1HTT | |
| SCHEMBL8102941 | 0.75 | MAPT (0.36) | ALDH1A1TDP1MEN1KMT2AP2RX1 | |
| SCHEMBL8098667 | 0.74 | HDAC1 (0.38) | PHOSPHO1 | |
| SCHEMBL16895171 | 0.69 | SLC6A9 (0.39) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL8099417 | 0.69 | ADRB1 (0.36) | MEN1KMT2A | |
| SCHEMBL15542522 | 0.69 | CYP2C9 (0.46) | ALDH1A1CYP3A4TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |