Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 3/20 | 0.55 |
| ▸ | BACE1 | P56817 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3614984 | 1.00 | ALDH1A1 (0.59) | ALDH1A1LMNAPOLBACHEBACE1 | |
| SCHEMBL4215258 | 0.89 | KDM1A (0.60) | ALDH1A1LMNAPOLBACHEBACE1 | |
| SCHEMBL5692019 | 0.89 | KDM1A (0.60) | ALDH1A1LMNAPOLBACHEBACE1 | |
| SCHEMBL22254428 | 0.89 | KDM1A (0.60) | ALDH1A1LMNAPOLBACHEBACE1 | |
| Hydrochloric Acid SCHEMBL4222870 | 0.88 | KDM1A (0.58) | ALDH1A1LMNAPOLBACHEBACE1 | |
| SCHEMBL82298 | 0.87 | ALDH1A1 (0.61) | ALDH1A1LMNAPOLBACHEBACE1 | |
| SCHEMBL1021686 | 0.83 | ALDH1A1 (0.60) | ALDH1A1ACHEBACE1MEN1KMT2A | |
| SCHEMBL3181878 | 0.83 | ALDH1A1 (0.63) | ALDH1A1LMNAACHEBACE1MEN1 | |
| SCHEMBL8275450 | 0.83 | HRH3 (0.76) | ALDH1A1LMNAPOLBACHEBACE1 | |
| SCHEMBL31612500 | 0.83 | ALDH1A1 (0.61) | ALDH1A1LMNAPOLBACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056744-A1 | 6,9-DISUBSTITUTED 2- TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | Aventis Pharmaceuticals Inc. (US) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999043675-A1 | 6,9-DISUBSTITUTED 2-[TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | AVENTIS PHARMACEUTICALS INC. (US) | 1999-09-02 | — | — | WO | disclosed |