SCHEMBL5692019

SCHEMBL5692019

Cc1ccc(CN2CCC(N)C2)cc1

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.60
ACHE P22303 2/20 0.54
BACE1 P56817 2/20 0.54
BCHE P06276 2/20 0.54
ALDH1A1 P00352 1/20 0.51
LMNA P02545 1/20 0.51
POLB P06746 1/20 0.51
HRH1 P35367 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
HRH3 Q9Y5N1 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
S1PR1 P21453 1/20 0.45
S1PR5 Q9H228 1/20 0.45
TEAD1 P28347 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4215258 1.00 KDM1A (0.60) KDM1AACHEBACE1BCHEALDH1A1
SCHEMBL22254428 1.00 KDM1A (0.60) KDM1AACHEBACE1BCHEALDH1A1
Hydrochloric Acid SCHEMBL4222870 0.98 KDM1A (0.58) KDM1AACHEBACE1BCHEALDH1A1
SCHEMBL22254436 0.90 DRD4 (0.51) KDM1AACHEBACE1BCHEALDH1A1
SCHEMBL22254446 0.90 DRD4 (0.51) KDM1AACHEBACE1BCHEALDH1A1
SCHEMBL3614984 0.89 ALDH1A1 (0.59) KDM1AACHEBACE1BCHEALDH1A1
SCHEMBL8099793 0.89 ALDH1A1 (0.59) KDM1AACHEBACE1BCHEALDH1A1
SCHEMBL22254429 0.89 KDM1A (0.50) KDM1AACHEBACE1BCHEALDH1A1
SCHEMBL22254430 0.85 S1PR1 (0.54) KDM1AACHEBACE1BCHEALDH1A1
SCHEMBL17450392 0.84 ALDH1A1 (0.55) KDM1AACHEBACE1BCHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060270847-A1 Process for producing nitrogenous heterocyclic compound TORAY FINE CHEMICALS CO., LTD. (JP) 2006-11-30 US claimed
EP-1640364-A1 PROCESS FOR PRODUCING NITROGENOUS HETEROCYCLIC COMPOUND Toray Fine Chemicals Co., Ltd. (JP) 2006-03-29 EP claimed
US-20060270847-A1 Process for producing nitrogenous heterocyclic compound TORAY FINE CHEMICALS CO., LTD. (JP) 2006-11-30 US disclosed
CN-1812970-A Process for producing nitrogenous heterocyclic compound TORAY FINECHEMICALS CO LTD (JP) 2006-08-02 CN disclosed
EP-1640364-A1 PROCESS FOR PRODUCING NITROGENOUS HETEROCYCLIC COMPOUND Toray Fine Chemicals Co., Ltd. (JP) 2006-03-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060270847-A1 Process for producing nitrogenous heterocyclic compound HNMT, HRH4, QDPR KDM1A 3779/4885ACHE 671/4885BACE1 1432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.