Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.54 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.54 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.48 |
| ▸ | PDE4A | P27815 | 2/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099888 | 0.96 | GPR119 (0.54) | GPR119SRD5A1CHEK2USP30PDE4D | |
| SCHEMBL8840797 | 0.87 | GPR119 (0.48) | GPR119SRD5A1CHEK2USP30PDE4D | |
| SCHEMBL18240934 | 0.85 | KDM4E (0.52) | GPR119CHEK2KDM4EPKM | |
| SCHEMBL5268593 | 0.84 | GPR119 (0.65) | GPR119CHEK2USP30KDM4EPKM | |
| SCHEMBL8840796 | 0.83 | GPR119 (0.48) | GPR119CHEK2USP30PDE4DPDE4A | |
| SCHEMBL1649132 | 0.83 | GPR119 (0.64) | GPR119SRD5A1CHEK2USP30PDE4D | |
| Hydrochloric Acid SCHEMBL14632585 | 0.82 | GPR119 (0.63) | GPR119SRD5A1CHEK2USP30PDE4D | |
| SCHEMBL1983176 | 0.81 | LMNA (0.59) | SRD5A1KDM4E | |
| SCHEMBL1375233 | 0.81 | GPR119 (0.54) | GPR119SRD5A1CHEK2USP30PDE4D | |
| SCHEMBL3345205 | 0.81 | GPR119 (0.64) | GPR119CHEK2USP30PDE4DPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |