Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10606206 | 1.00 | TSHR (0.51) | TSHRALDH1A1GAAEPHX2SMN1; SMN2 | |
| SCHEMBL10501285 | 1.00 | TSHR (0.51) | TSHRALDH1A1GAAEPHX2SMN1; SMN2 | |
| SCHEMBL4944206 | 0.84 | CYP1A2 (0.49) | ALDH1A1GAASMN1; SMN2CYP1A2L3MBTL1 | |
| SCHEMBL5037810 | 0.84 | CYP1A2 (0.49) | ALDH1A1GAASMN1; SMN2CYP1A2L3MBTL1 | |
| SCHEMBL4940078 | 0.84 | CYP1A2 (0.49) | ALDH1A1GAASMN1; SMN2CYP1A2L3MBTL1 | |
| SCHEMBL5038849 | 0.81 | DGKA (0.42) | TSHRALDH1A1EPHX2SMN1; SMN2TDP1 | |
| SCHEMBL562999 | 0.81 | TSHR (0.47) | TSHRALDH1A1EPHX2SMN1; SMN2LMNA | |
| SCHEMBL563000 | 0.81 | TSHR (0.47) | TSHRALDH1A1EPHX2SMN1; SMN2LMNA | |
| SCHEMBL4941280 | 0.81 | TSHR (0.47) | TSHRALDH1A1EPHX2SMN1; SMN2LMNA | |
| SCHEMBL5037088 | 0.80 | DGKA (0.45) | TSHRALDH1A1EPHX2TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124473-A | ENANTIOMERIC RESOLUTION IS CARRIED OUT BY SIMULATED MOBILE BED CHROMATOGRAPHY, USING AT LEAST THREE COLUMNS FILLED WITH CHIRAL STATIONARY PHASE. | UCB, S.A. (BE) | 2000-09-26 | — | — | US | disclosed |