Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5037088 | 0.93 | DGKA (0.45) | DGKAPRSS1PRSS2PRSS3EPHX2 | |
| SCHEMBL5038851 | 0.90 | PRSS1 (0.51) | DGKAPRSS1PRSS2PRSS3EPHX2 | |
| SCHEMBL4940078 | 0.88 | CYP1A2 (0.49) | TOP2AALDH1A1CYP3A4L3MBTL1KDM4E | |
| SCHEMBL5037810 | 0.88 | CYP1A2 (0.49) | TOP2AALDH1A1CYP3A4L3MBTL1KDM4E | |
| SCHEMBL4944206 | 0.88 | CYP1A2 (0.49) | TOP2AALDH1A1CYP3A4L3MBTL1KDM4E | |
| SCHEMBL562999 | 0.84 | TSHR (0.47) | EPHX2ALDH1A1LMNATSHRL3MBTL1 | |
| SCHEMBL4941280 | 0.84 | TSHR (0.47) | EPHX2ALDH1A1LMNATSHRL3MBTL1 | |
| SCHEMBL563000 | 0.84 | TSHR (0.47) | EPHX2ALDH1A1LMNATSHRL3MBTL1 | |
| SCHEMBL5037886 | 0.84 | MAPT (0.40) | EPHX2ALDH1A1LMNACYP3A4TSHR | |
| SCHEMBL5037770 | 0.83 | CYP3A4 (0.49) | ALDH1A1LMNACYP3A4TSHRATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339669-B1 | N-ALKYLATED GABA COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | UCB PHARMA SA (BE) | 2008-06-04 | — | — | EP | claimed |
| US-7112612-B2 | N-alkylated GABA compounds, processes for their preparation and their use as medicaments | UCB S.A. (BE) | 2006-09-26 | — | — | US | claimed |
| US-20040058991-A1 | N-alkylated gaba compounds, processes for their preparation and their use as medicaments | UCB S.A. (BE) | 2004-03-25 | — | — | US | claimed |
| EP-1339669-B1 | N-ALKYLATED GABA COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | UCB PHARMA SA (BE) | 2008-06-04 | — | — | EP | disclosed |
| US-7112612-B2 | N-alkylated GABA compounds, processes for their preparation and their use as medicaments | UCB S.A. (BE) | 2006-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058991-A1 | N-alkylated gaba compounds, processes for their preparation and their use as medicaments | GABBR1, GABRB1, GABRB2 | DGKA 1229/4885TOP2A 3341/4885PRSS1 4716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.