Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 known ✓ | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 known ✓ | P41145 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 5/20 | 0.40 |
| ▸ | MMP9 | P14780 | 5/20 | 0.40 |
| ▸ | MMP8 | P22894 | 3/20 | 0.40 |
| ▸ | MMP13 | P45452 | 3/20 | 0.40 |
| ▸ | MMP3 | P08254 | 2/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL7176236 | 0.99 | MMP2 (0.39) | MMP2MMP9MMP8MMP13MMP3 | |
| SCHEMBL1878427 | 0.92 | MMP2 (0.42) | MMP2MMP9MMP8MMP13MMP3 | |
| SCHEMBL287632 | 0.92 | MMP2 (0.42) | MMP2MMP9MMP8MMP13MMP3 | |
| SCHEMBL498620 | 0.92 | MMP2 (0.42) | MMP2MMP9MMP8MMP13MMP3 | |
| SCHEMBL289725 | 0.92 | MMP2 (0.42) | MMP2MMP9MMP8MMP13MMP3 | |
| Sulfuric Acid SCHEMBL9796195 | 0.91 | MMP2 (0.39) | MMP2MMP9MMP8MMP13MMP3 | |
| Phosphoric Acid SCHEMBL8199833 | 0.90 | CETP (0.40) | MMP2MMP9MMP8MMP13MMP3 | |
| Acrylic Acid SCHEMBL4921583 | 0.86 | ZDHHC2 (0.39) | MMP2MMP9MMP8MMP13MMP3 | |
| Methyl Alcohol SCHEMBL11123438 | 0.81 | MMP2 (0.42) | MMP2MMP9MMP8MMP13MMP3 | |
| SCHEMBL11499462 | 0.81 | MMP2 (0.44) | MMP2MMP9MMP8MMP13MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3085715-A1 | POLYORGANOSILOXANE-CONTAINING GRAFT COPOLYMER, RESIN COMPOSITION, AND MOLDED ARTICLE | Mitsubishi Rayon Co., Ltd. (JP) | 2016-10-26 | — | — | EP | disclosed |
| EP-2915828-A2 | POLYORGANOSILOXANE-CONTAINING GRAFT COPOLYMER, RESIN COMPOSITION, AND MOLDED ARTICLE | Mitsubishi Rayon Co., Ltd. (JP) | 2015-09-09 | — | — | EP | disclosed |
| US-6066660-A | 1-SUBSTITUTED PHENYLPYRAZOLE INSECTICIDE OF GIVEN FORMULA, PYRETHROID, WEAKLY POLAR SOLVENT, AN EMULSIFYING AGENT AND A WATER SOLUBLE SOLVENT; CAN BE DILUTED WITHOUT FORMING CRYSTALS | RHONE-POULENC AGROCHIMIE (FR) | 2000-05-23 | — | — | US | disclosed |
| EP-0794701-B1 | EMULSIFIABLE COMPOSITION FOR THE CONTROL OF INSECTS | RHONE POULENC AGROCHIMIE (FR) | 2000-01-26 | — | — | EP | disclosed |
| EP-0794701-A2 | EMULSIFIABLE COMPOSITION FOR THE CONTROL OF INSECTS | RHONE-POULENC AGROCHIMIE (FR) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996016543-A2 | EMULSIFIABLE COMPOSITION FOR THE CONTROL OF INSECTS | RHONE-POULENC AGROCHIMIE (FR) | 1996-06-06 | — | — | WO | disclosed |