Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.49 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.47 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099803 | 0.88 | NPC1 (0.51) | GRIN1GRIN2AALDH1A1KDM4ERXFP1 | |
| SCHEMBL8092460 | 0.85 | GRIN1 (0.55) | GRIN1GRIN2AKDM5BALDH1A1KDM4E | |
| SCHEMBL1660663 | 0.85 | NPC1 (0.56) | GRIN1GRIN2AALDH1A1KDM4ENPC1 | |
| SCHEMBL8102158 | 0.84 | NR1H4 (0.50) | GRIN1GRIN2AKDM5BPIM1GSK3B | |
| SCHEMBL8099894 | 0.82 | MEN1 (0.52) | ALDH1A1KDM4ENPC1RAB9AHPGD | |
| SCHEMBL8102213 | 0.82 | RAD51 (0.56) | GRIN1GRIN2AALDH1A1KDM4ERXFP1 | |
| SCHEMBL32688368 | 0.81 | ALDH1A3 (0.50) | GRIN1GRIN2AALDH1A1KDM4ENPC1 | |
| SCHEMBL32688108 | 0.80 | GAA (0.53) | GRIN1GRIN2AKDM4ERXFP1PKM | |
| SCHEMBL8099857 | 0.80 | NR1H4 (0.50) | GRIN1GRIN2AALDH1A1KDM4ERXFP1 | |
| SCHEMBL31365868 | 0.80 | KDM5B (0.50) | GRIN1GRIN2AKDM5BCDC7PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100263-A | CONTROLLING ANIMAL PESTS OR HARMFUL FUNGI; 2-METHOXYIMINO-2-(2'-(1?-METHYL,1?-(1?'-(6??-(4??'-CHLOROPHENYL) -HEXYLOXYIMINO) ,2?',2?'-DIMETHYLPROPYL))IMINOOXYMETHYL)-PHENYLACETIC ACID MONOMETHYLAMIDE, FOR EXAMPLE | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-08 | — | — | US | disclosed |
| US-6071930-A | FOR INHIBITION OF MITOSIS OR TUMOR GROWTH | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2000-06-06 | — | — | US | disclosed |
| US-5994367-A | PREVENT CELL MITOSIS; ANTICARCINOGENIC AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1999-11-30 | — | — | US | disclosed |