Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 8/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | HTR2B | P41595 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8110702 | 0.91 | PPOX (0.50) | PPOXPOLBHTR2CHTR2BHTR2A | |
| SCHEMBL8110190 | 0.87 | PPOX (0.36) | PPOXPOLBGAAPKMMAPT | |
| SCHEMBL8116097 | 0.82 | POLB (0.34) | PPOXPOLBGAAPKMHTR2C | |
| SCHEMBL8110444 | 0.81 | GAA (0.34) | PPOXPOLBGAAPKMHTR2C | |
| SCHEMBL8110364 | 0.79 | PPOX (0.46) | PPOX | |
| SCHEMBL8110417 | 0.79 | PPOX (0.40) | PPOXPOLB | |
| SCHEMBL8110674 | 0.76 | PPOX (0.35) | PPOXPOLBMAPT | |
| SCHEMBL8110461 | 0.74 | PPOX (0.39) | PPOXPOLBMAPT | |
| SCHEMBL8100657 | 0.74 | PPOX (0.35) | PPOXPOLBMAPT | |
| SCHEMBL8110127 | 0.74 | PPOX (0.35) | PPOXPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780385-B1 | Arylthiadiazolones with a herbicidal activity | ISAGRO RICERCA SRL (IT) | 2000-05-10 | — | — | EP | disclosed |
| US-5821197-A | CYCLIZATION OF A THIOHYDRAZIDE | ISAGRO RICERCA S.R.L. (IT) | 1998-10-13 | — | — | US | disclosed |
| EP-0780385-A1 | Arylthiadiazolones with a herbicidal activity | ISAGRO RICERCA S.r.l. (IT) | 1997-06-25 | — | — | EP | disclosed |