SCHEMBL8101050

SCHEMBL8101050

CCCCCCCCCCCCCCCCCCNCCOCCO

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
THRB P10828 1/20 0.61
HTT P42858 1/20 0.61
MAPT P10636 1/20 0.61
TSHR P16473 5/20 0.56
ALDH1A1 P00352 3/20 0.52
S1PR2 O95136 5/20 0.44
S1PR4 O95977 5/20 0.44
S1PR1 P21453 5/20 0.44
S1PR3 Q99500 5/20 0.44
S1PR5 Q9H228 1/20 0.44
EPHX2 P34913 1/20 0.43
LMNA P02545 3/20 0.41
MAPK1 P28482 2/20 0.41
USP2 O75604 1/20 0.41
CYP3A4 P08684 1/20 0.41
CASP1 P29466 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
SLCO1B3 Q9NPD5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8101026 1.00 MEN1 (0.61) MEN1KMT2ATHRBHTTMAPT
SCHEMBL14010914 1.00 MEN1 (0.61) MEN1KMT2ATHRBHTTMAPT
SCHEMBL817981 1.00 MEN1 (0.61) MEN1KMT2ATHRBHTTMAPT
SCHEMBL8113758 1.00 MEN1 (0.61) MEN1KMT2ATHRBHTTMAPT
SCHEMBL8219819 0.98 MEN1 (0.64) MEN1KMT2ATHRBHTTMAPT
SCHEMBL11347984 0.98 MEN1 (0.64) MEN1KMT2ATHRBHTTMAPT
SCHEMBL11350056 0.98 MEN1 (0.64) MEN1KMT2ATHRBHTTMAPT
SCHEMBL11344130 0.98 MEN1 (0.64) MEN1KMT2ATHRBHTTMAPT
SCHEMBL11344512 0.98 MEN1 (0.64) MEN1KMT2ATHRBHTTMAPT
SCHEMBL13538736 0.98 MEN1 (0.64) MEN1KMT2ATHRBHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101717554-B Plastic profiled bar decorative layer combination material with metal-like natural texture, preparation method and application thereof GUANGDONG SHENGHENGCHANG CHEMICAL INDUSTRY CO LTD 2013-09-25 CN claimed
CN-101717554-A Plastic profiled bar decorative layer combination material with metal-like natural texture, preparation method and application thereof GUANGDONG SHENGHENGCHANG CHEMI 2010-06-02 CN claimed
WO-2021252290-A2 COMPOSITIONS AND METHODS FOR TREATING NOVEL CORONAVIRUS SARS-COV-2-MEDIATED INFLAMMATORY CONDITIONS GRI BIO, INC. (US) 2021-12-16 WO disclosed
EP-3229811-B1 PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS GRI BIO INC (US) 2021-02-24 EP disclosed
EP-3229811-B1 PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS GRI BIO INC (US) 2021-02-24 EP disclosed
US-20160158258-A1 PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS ALTIUM GROWTH FUND, LP 2016-06-09 US disclosed
CN-101717554-B Plastic profiled bar decorative layer combination material with metal-like natural texture, preparation method and application thereof GUANGDONG SHENGHENGCHANG CHEMICAL INDUSTRY CO LTD 2013-09-25 CN disclosed
CN-101717554-A Plastic profiled bar decorative layer combination material with metal-like natural texture, preparation method and application thereof GUANGDONG SHENGHENGCHANG CHEMI 2010-06-02 CN disclosed
US-6060612-A SKIN CARE COSMETIC PACIFIC CORPORATION (KR) 2000-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160158258-A1 PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS RXRA, RXRG, CX3CR1 MEN1 4785/4885KMT2A 411/4885THRB 3055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.