Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13116021 | 0.81 | ALDH1A1 (0.60) | CACNA1BAPBA1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL5502887 | 0.80 | CACNA1B (0.61) | CACNA1BAPBA1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL3786785 | 0.80 | RAB9A (0.54) | SMN1; SMN2HTTALDH1A1KMT2AMEN1 | |
| SCHEMBL10496871 | 0.78 | ALDH1A1 (0.50) | CACNA1BAPBA1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL5505094 | 0.78 | NAMPT (0.58) | CACNA1BAPBA1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL12368426 | 0.77 | ALDH1A1 (0.65) | CACNA1BAPBA1SMN1; SMN2HTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL10390651 | 0.77 | MEN1 (0.49) | CACNA1BAPBA1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL17633861 | 0.75 | CACNA1B (0.54) | CACNA1BAPBA1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL14880210 | 0.75 | CACNA1B (0.67) | CACNA1BAPBA1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL13210697 | 0.74 | CACNA1B (0.85) | CACNA1BAPBA1SMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734526-A4 | MALEIMIDE ADDUCT CONJUGATES OF PROCAINAMIDE AND NAPA | ROCHE DIAGNOSTICS CORP (US) | 2000-03-29 | — | — | EP | disclosed |
| EP-0734526-A1 | MALEIMIDE ADDUCT CONJUGATES OF PROCAINAMIDE AND NAPA | BOEHRINGER MANNHEIM CORPORATION (US) | 1996-10-02 | — | — | EP | disclosed |
| US-5439798-A | Immunoassay; competitive binding; quantitative analysis | BOEHRINGER MANNHEIM CORPORATION (US) | 1995-08-08 | — | — | US | disclosed |
| WO-1995016894-A1 | MALEIMIDE ADDUCT CONJUGATES OF PROCAINAMIDE AND NAPA | BOEHRINGER MANNHEIM CORPORATION (US) | 1995-06-22 | — | — | WO | disclosed |