Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8101416 | 0.94 | THRB (0.41) | ALDH1A1THRBLMNAHTTSMN1; SMN2 | |
| SCHEMBL8101420 | 0.94 | THRB (0.41) | ALDH1A1THRBLMNAHTTSMN1; SMN2 | |
| SCHEMBL29618128 | 0.88 | TSHR (0.31) | ALDH1A1EPHX2EPHX1NPC1 | |
| SCHEMBL2112114 | 0.79 | TSHR (0.31) | ALDH1A1EPHX2EPHX1NPC1 | |
| SCHEMBL5917758 | 0.79 | THRB (0.37) | ALDH1A1THRBLMNAHTTSMN1; SMN2 | |
| SCHEMBL2741163 | 0.78 | ALDH1A1 (0.36) | ALDH1A1LMNASMN1; SMN2EPHX2 | |
| SCHEMBL2741160 | 0.76 | KMT2A (0.31) | SMN1; SMN2 | |
| SCHEMBL5917724 | 0.75 | ALDH1A1 (0.38) | ALDH1A1THRBLMNAHTTSMN1; SMN2 | |
| SCHEMBL5917760 | 0.74 | THRB (0.45) | ALDH1A1THRBLMNAHTTSMN1; SMN2 | |
| SCHEMBL5917763 | 0.74 | THRB (0.45) | ALDH1A1THRBLMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006130-A1 | Fumaric acid diester resin composition, cross-linked fumaric acid diester resin and process | NOF CORPORATION (JP) | 2000-06-07 | — | — | EP | disclosed |