Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.59 |
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.54 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.54 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.54 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3765344 | 0.87 | CCR3 (0.57) | CCR3CARM1PRMT6PRMT3PRMT1 | |
| SCHEMBL595263 | 0.83 | GBA1 (0.59) | CCR3ACHECARM1PRMT6PRMT3 | |
| SCHEMBL8776715 | 0.81 | CCR3 (0.57) | CCR3CARM1PRMT6PRMT3PRMT1 | |
| SCHEMBL8481226 | 0.81 | GBA1 (0.68) | CCR3CARM1PRMT6PRMT3PRMT1 | |
| SCHEMBL327856 | 0.79 | CCR3 (0.66) | CCR3CARM1PRMT6PRMT3PRMT1 | |
| Hydrochloric Acid SCHEMBL8483895 | 0.79 | GBA1 (0.66) | CCR3CARM1PRMT6PRMT3PRMT1 | |
| SCHEMBL7698046 | 0.76 | CCR3 (0.71) | CCR3CARM1PRMT6PRMT3PRMT1 | |
| SCHEMBL3981456 | 0.76 | CCR3 (0.61) | CCR3CARM1PRMT6PRMT3PRMT1 | |
| SCHEMBL6570399 | 0.76 | GBA1 (0.52) | CCR3ACHECARM1PRMT6PRMT3 | |
| SCHEMBL2027845 | 0.76 | GBA1 (0.71) | CCR3CARM1PRMT6PRMT3PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973936-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998046786-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| WO-1998008839-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED THIOPHENE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |