Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 13/20 | 0.42 |
| ▸ | MITF | O75030 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11360578 | 0.86 | GSK3B (0.42) | GSK3BMITFMAPTALDH1A1LMNA | |
| SCHEMBL9064055 | 0.82 | ALDH1A1 (0.46) | GSK3BMITFMAPTALDH1A1LMNA | |
| SCHEMBL23071761 | 0.78 | ALDH1A1 (0.38) | GSK3BMITFMAPTALDH1A1LMNA | |
| SCHEMBL23071750 | 0.78 | ALDH1A1 (0.38) | GSK3BMITFMAPTALDH1A1LMNA | |
| SCHEMBL29463755 | 0.78 | ALDH1A1 (0.38) | GSK3BMITFMAPTALDH1A1LMNA | |
| SCHEMBL23071749 | 0.74 | KMT2A (0.36) | GSK3BMITFMAPTALDH1A1LMNA | |
| SCHEMBL5037304 | 0.73 | ALDH1A1 (0.39) | MAPTALDH1A1MAPK1SMN1; SMN2KDM4E | |
| SCHEMBL6063144 | 0.73 | GSK3B (0.50) | GSK3BMITFMAPTALDH1A1LMNA | |
| SCHEMBL16632821 | 0.72 | ALDH1A1 (0.54) | MAPTALDH1A1LMNARAB9AKMT2A | |
| SCHEMBL8106142 | 0.70 | CYP3A4 (0.54) | MAPTALDH1A1KMT2ANPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601413-B1 | Method for the productin of Arene bisphosphinoxides | BASF AG (DE) | 2000-01-26 | — | — | EP | disclosed |
| US-5410060-A | Haloacetylation, carboxylation, phosphination | BASF AKTIENGESELLSCHAFT (DE) | 1995-04-25 | — | — | US | disclosed |
| EP-0601413-A1 | Arene bisphosphinoxides | BASF Aktiengesellschaft (DE) | 1994-06-15 | — | — | EP | disclosed |