Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1271967 | 0.78 | MAP3K14 (0.51) | ADRA2ALMNAMAPTHTTBLM | |
| SCHEMBL24916258 | 0.76 | ADRA2A (0.51) | ADRA2ALMNAMAPTHTTBLM | |
| SCHEMBL8139370 | 0.76 | ITGB2 (0.41) | LMNAHTTMAP3K14MAOBMAPK1 | |
| SCHEMBL30134460 | 0.76 | ADRA2A (0.51) | ADRA2ALMNAMAPTHTTBLM | |
| SCHEMBL4142656 | 0.75 | ADRA2A (0.50) | ADRA2ALMNAMAPTHTTBLM | |
| SCHEMBL25202695 | 0.75 | ADRA2A (0.50) | ADRA2ALMNAMAPTHTTBLM | |
| SCHEMBL27817330 | 0.74 | ADRA2A (0.47) | ADRA2ALMNAMAPTHTTBLM | |
| Hydrochloric Acid SCHEMBL21810776 | 0.73 | ADRA2A (0.49) | ADRA2ALMNAMAPTHTTBLM | |
| Hydrochloric Acid SCHEMBL27159672 | 0.73 | ADRA2A (0.49) | ADRA2ALMNAMAPTHTTBLM | |
| SCHEMBL1843412 | 0.73 | ADRA2A (0.46) | ADRA2ALMNAMAPTHTTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1031572-A1 | PYRIDYLPYRROLE DERIVATIVES | Sankyo Company Limited (JP) | 2000-08-30 | — | — | EP | disclosed |