Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30134460 | 1.00 | ADRA2A (0.51) | ADRA2ALMNAMAPTHTTBLM | |
| SCHEMBL4142656 | 0.80 | ADRA2A (0.50) | ADRA2ALMNAMAPTHTTBLM | |
| SCHEMBL1271967 | 0.80 | MAP3K14 (0.51) | ADRA2ALMNAMAPTHTTBLM | |
| SCHEMBL25202695 | 0.80 | ADRA2A (0.50) | ADRA2ALMNAMAPTHTTBLM | |
| Hydrochloric Acid SCHEMBL21810776 | 0.79 | ADRA2A (0.49) | ADRA2ALMNAMAPTHTTBLM | |
| Hydrochloric Acid SCHEMBL27159672 | 0.79 | ADRA2A (0.49) | ADRA2ALMNAMAPTHTTBLM | |
| SCHEMBL2114089 | 0.77 | ADRA2A (0.48) | ADRA2ALMNAMAPTHTTBLM | |
| SCHEMBL24915792 | 0.76 | ENPP2 (0.48) | MAPTDRD2DRD3NPC1RAB9A | |
| SCHEMBL23704789 | 0.76 | ADRA2A (0.47) | ADRA2ALMNAMAPTHTTBLM | |
| SCHEMBL8101883 | 0.76 | ADRA2A (0.47) | ADRA2ALMNAMAPTHTTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | ADRA2A 4703/4885LMNA 3551/4885MAPT 1413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.