SCHEMBL810200

SCHEMBL810200

CONC(=O)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.61
POLB P06746 1/20 0.61
MAPT P10636 1/20 0.61
KMT2A Q03164 1/20 0.61
TSHR P16473 1/20 0.58
RAB9A P51151 8/20 0.55
NPC1 O15118 7/20 0.55
HDAC3 O15379 1/20 0.54
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
IDO1 P14902 1/20 0.54
ALOX15 P16050 1/20 0.54
HDAC1 Q13547 1/20 0.54
CA9 Q16790 1/20 0.54
HDAC7 Q8WUI4 1/20 0.54
HDAC2 Q92769 1/20 0.54
HSD17B10 Q99714 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
NCOR2 Q9Y618 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL27455549 0.98 ALDH1A1 (0.59) ALDH1A1POLBMAPTKMT2ATSHR
Hydrochloric Acid SCHEMBL28193464 0.98 ALDH1A1 (0.59) ALDH1A1POLBMAPTKMT2ATSHR
SCHEMBL28325726 0.89 ALDH1A1 (0.55) ALDH1A1POLBMAPTKMT2ATSHR
Trifluoroacetic Acid SCHEMBL27745019 0.89 POLB (0.50) ALDH1A1POLBMAPTKMT2ATSHR
SCHEMBL7427811 0.88 CTDSP1 (0.60) ALDH1A1POLBMAPTKMT2ARAB9A
SCHEMBL31174586 0.85 MAPT (0.46) ALDH1A1POLBMAPTKMT2ATSHR
SCHEMBL28761123 0.85 PARP10 (0.59) TSHRRAB9ANPC1HDAC3CA12
SCHEMBL17336876 0.83 HDAC8 (0.64) ALDH1A1POLBMAPTKMT2ARAB9A
SCHEMBL11497918 0.81 ALDH1A1 (0.65) ALDH1A1POLBMAPTKMT2ATSHR
SCHEMBL10763263 0.81 MAPT (0.46) ALDH1A1POLBMAPTKMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 455 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114929669-B Aryl amide derivatives with antitumor activity 中外制药株式会社 2024-11-29 CN claimed
CN-118955564-A DOPO phosphoramide derivative flame retardant, preparation method thereof and application thereof in waterborne polyurethane 浙江理工大学 2024-11-15 CN claimed
CN-118772064-A Pyrimidine compound containing nitrogen methoxy benzamide and preparation method and application thereof 贵州大学 2024-10-15 CN claimed
CN-113735756-B Method for synthesizing chiral 3, 3-disubstituted isoindolinone compound by rhodium catalysis 陕西师范大学 2024-04-26 CN claimed
WO-2023240271-A1 USE OF VEGFR2 AND FGFR1 INHIBITORS IN THERAPY FOUNTAIN THERAPEUTICS INC. (US) 2023-12-14 WO claimed
CN-116768745-A Synthesis method of photoinduction N-aryl benzamide compound 中国科学院大连化学物理研究所 2023-09-19 CN claimed
CN-115260136-B Phthalide compound and preparation method thereof 嘉兴学院 2023-08-15 CN claimed
CN-113149868-B Method for synthesizing axichiral diene compound by trivalent rhodium catalysis 陕西师范大学 2023-05-23 CN claimed
CN-115260136-A Phthalide compound and preparation method thereof 嘉兴学院 2022-11-01 CN claimed
CN-114929669-A Arylamide derivatives having antitumor activity 中外制药株式会社 2022-08-19 CN claimed
CN-1837202-A Flavonols with blood-fat-lowering effect UNIV PLA 2ND MILITARY MEDICAL (CN) 2006-09-27 CN claimed
WO-2005113494-A2 NITROGENATED HETEROCYCLIC DERIVATIVES AS PROTEIN KINASE MODULATORS AND USE FOR THE TREATMENT OF ANGIOGENESIS AND CANCER AMGEN INC. (US) 2005-12-01 WO claimed
CN-1087737-C Dihygropyridine derivatives as bradykinin antagonists PFIZER (US) 2002-07-17 CN claimed
CN-1156449-A Dihygropyridine derivatives as bradykinin antagonists PFIZER (US) 1997-08-06 CN claimed
EP-0088729-B1 USE OF METAL COMPLEXES OF HYDRAZONES AS PIGMENTS CIBA-GEIGY AG (CH) 1987-07-29 EP claimed
US-4617401-A ANTISPASMODIC AGENTS, VASODILATORS SUNTORY LTD. (JP) 1986-10-14 US claimed
US-4612014-A Use of metal complexes of hydrazones as pigments CIBA-GEIGY CORPORATION (US) 1986-09-16 US claimed
EP-0088729-A1 Use of metal complexes of hydrazones as pigments CIBA-GEIGY AG (CH) 1983-09-14 EP claimed
US-4153608-A Anthraquinone vat dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1979-05-08 US claimed
US-4016263-A BACTERICIDES BOEHRINGER INGELHEIM GMBH (DT) 1977-04-05 US claimed