Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810200 | 0.81 | ALDH1A1 (0.61) | MAPTCA1NPC1RAB9AALDH1A1 | |
| SCHEMBL28325726 | 0.79 | ALDH1A1 (0.55) | MAPTCA1NPC1RAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL28193464 | 0.79 | ALDH1A1 (0.59) | MAPTCA1NPC1RAB9AALDH1A1 | |
| Fluoride SCHEMBL27455549 | 0.79 | ALDH1A1 (0.59) | MAPTCA1NPC1RAB9AALDH1A1 | |
| SCHEMBL28647585 | 0.79 | MAPT (0.50) | MAPTCA1CA2RAB9AALDH1A1 | |
| SCHEMBL27951738 | 0.79 | MAPT (0.70) | MAPTCA1CA2NPC1RAB9A | |
| SCHEMBL14602517 | 0.79 | LMNA (0.55) | MAPTCA1CA2CYP2C19CYP1A2 | |
| SCHEMBL3645797 | 0.79 | ALDH1A1 (0.61) | MAPTNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL9402939 | 0.79 | CA1 (0.59) | MAPTCA1CA2CYP3A4PKM | |
| SCHEMBL7427811 | 0.78 | CTDSP1 (0.60) | MAPTCYP3A4NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212404-A1 | 7-oxo-4-thia-1-azabicyclo [3.2.0] hept-2-ene derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-04 | — | — | EP | disclosed |