Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.62 |
| ▸ | DGAT2 | Q96PD7 | 6/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | ITK | Q08881 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MGAT2 | Q10469 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7003204 | 0.84 | SLC9A1 (0.67) | SLC9A1DGAT2HTR2AHTR2CHTR2B | |
| SCHEMBL10288769 | 0.84 | SLC9A1 (0.67) | SLC9A1DGAT2HTR2AHTR2CHTR2B | |
| SCHEMBL8357586 | 0.84 | SLC9A1 (0.67) | SLC9A1DGAT2HTR2AHTR2CHTR2B | |
| SCHEMBL21501023 | 0.84 | SLC9A1 (0.67) | SLC9A1DGAT2HTR2AHTR2CHTR2B | |
| SCHEMBL1207144 | 0.84 | SLC9A1 (0.67) | SLC9A1DGAT2HTR2AHTR2CHTR2B | |
| SCHEMBL24737951 | 0.84 | SLC9A1 (0.67) | SLC9A1DGAT2HTR2AHTR2CHTR2B | |
| SCHEMBL7003208 | 0.84 | SLC9A1 (0.67) | SLC9A1DGAT2HTR2AHTR2CHTR2B | |
| SCHEMBL30997748 | 0.82 | SLC9A1 (0.73) | SLC9A1DGAT2HTR2AHTR2CHTR2B | |
| SCHEMBL6326088 | 0.80 | SLC9A1 (0.62) | SLC9A1DGAT2HTR2AHTR2CHTR2B | |
| SCHEMBL16328165 | 0.79 | SLC9A1 (0.52) | SLC9A1DGAT2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747346-B1 | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL MYERS SQUIBB CO (US) | 2000-02-16 | — | — | EP | disclosed |
| EP-0747346-A2 | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |