Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631582 | 0.73 | RAB9A (0.33) | HTR2AHTR2CHTR2BRAB9AOPRM1 | |
| SCHEMBL3747979 | 0.70 | BACE1 (0.39) | HTR2AHTR2CHTR2BRAB9ACA2 | |
| SCHEMBL30714239 | 0.70 | BACE1 (0.39) | HTR2AHTR2CHTR2BRAB9ACA2 | |
| SCHEMBL27416207 | 0.68 | HTR2A (0.33) | HTR2AHTR2CHTR2BRAB9ACA1 | |
| SCHEMBL9187689 | 0.68 | KDM1A (0.38) | HTR2AHTR2CHTR2BKDM1AADRA2A | |
| SCHEMBL7418018 | 0.67 | PNMT (0.38) | HTR2AHTR2CHTR2BKDM1ASLC6A4 | |
| SCHEMBL30016697 | 0.66 | KDM1A (0.44) | HTR2AHTR2CKDM1AKDM1BSLC6A2 | |
| SCHEMBL13799423 | 0.66 | PNMT (0.43) | HTR2AHTR2CHTR2BOPRM1OPRK1 | |
| SCHEMBL10196253 | 0.66 | HTR2A (0.41) | HTR2AHTR2CHTR2BRAB9ACA1 | |
| SCHEMBL31064331 | 0.66 | HTR2A (0.35) | HTR2AHTR2CHTR2BCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1031572-A1 | PYRIDYLPYRROLE DERIVATIVES | Sankyo Company Limited (JP) | 2000-08-30 | — | — | EP | disclosed |