Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | PTPRC | P08575 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3406520 | 0.74 | MEN1 (0.47) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8102187 | 0.70 | RAB9A (0.51) | CDC25BCDC25AMAPTALDH1A1MEN1 | |
| SCHEMBL30139895 | 0.69 | CDC25B (0.46) | CDC25BCDC25AMAPTLMNAALDH1A1 | |
| SCHEMBL3444897 | 0.68 | CDC25B (0.57) | CDC25BCDC25AMAPTLMNAALDH1A1 | |
| SCHEMBL8102460 | 0.67 | CDC25A (0.47) | CDC25BCDC25AMAPTLMNAALDH1A1 | |
| SCHEMBL8108519 | 0.67 | MAPT (0.51) | CDC25BCDC25AMAPTLMNAALDH1A1 | |
| SCHEMBL8731780 | 0.67 | CDC25B (0.52) | CDC25BCDC25AMAPTLMNAALDH1A1 | |
| SCHEMBL10336571 | 0.65 | CDC25A (0.33) | CDC25BCDC25ALMNACYP1A2 | |
| Ammonia Solution, Strong SCHEMBL27851299 | 0.65 | CDC25B (0.50) | CDC25BCDC25AMAPTLMNAALDH1A1 | |
| Formic Acid SCHEMBL31606783 | 0.65 | MAPT (0.52) | CDC25BCDC25AMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013674-A | INDENONE AMIDE DERIVATIVES, USEFUL FOR FOR THE INHIBITION OF LEUKOCYTE ADHERENCE TO ENDOTHELIAL CELLS; USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES, AS ARTHRITIS, ASTHAMA, PSORIASIS, RESPIRATORY DISTRESS SYNDROME, STROKE AND ULCER | ELI LILLY AND COMPANY (US) | 2000-01-11 | — | — | US | disclosed |
| EP-0882706-A1 | Cell adhesion inhibitors | ELI LILLY AND COMPANY (US) | 1998-12-09 | — | — | EP | disclosed |