Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | MDM4 | O15151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15690474 | 0.85 | HDAC6 (0.62) | CDC25ACDC25BTDP2G6PDPAX8 | |
| SCHEMBL8102187 | 0.81 | RAB9A (0.51) | CDC25ACDC25BTDP2G6PDPAX8 | |
| SCHEMBL8108519 | 0.77 | MAPT (0.51) | CDC25ACDC25BTDP2G6PDPAX8 | |
| SCHEMBL8102486 | 0.75 | TDP2 (0.54) | TDP2PAX8HKDC1ALDH1A1TP53 | |
| SCHEMBL18347803 | 0.74 | S100A4 (0.58) | CDC25BTDP2G6PDPAX8HKDC1 | |
| SCHEMBL8108363 | 0.73 | SOAT1 (0.47) | TDP2PAX8HKDC1ALDH1A1MEN1 | |
| SCHEMBL8106472 | 0.70 | DHODH (0.49) | TDP2ALDH1A1TP53MDM4MEN1 | |
| SCHEMBL8102448 | 0.70 | HSP90AA1 (0.47) | TDP2PAX8HKDC1ALDH1A1TP53 | |
| SCHEMBL13391074 | 0.69 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL8100811 | 0.69 | HSP90AA1 (0.46) | CDC25ACDC25BTDP2PAX8HKDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013674-A | INDENONE AMIDE DERIVATIVES, USEFUL FOR FOR THE INHIBITION OF LEUKOCYTE ADHERENCE TO ENDOTHELIAL CELLS; USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES, AS ARTHRITIS, ASTHAMA, PSORIASIS, RESPIRATORY DISTRESS SYNDROME, STROKE AND ULCER | ELI LILLY AND COMPANY (US) | 2000-01-11 | — | — | US | disclosed |
| EP-0882706-A1 | Cell adhesion inhibitors | ELI LILLY AND COMPANY (US) | 1998-12-09 | — | — | EP | disclosed |