SCHEMBL81025

SCHEMBL81025

C=C(C)C(=O)OCCCC(C)O[Si](C)(OCC)OCC

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
THRB P10828 1/20 0.44
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4100963 0.89 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL27635964 0.89 TSHR (0.45) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28044455 0.87 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL31709677 0.86 TSHR (0.44) TSHRTHRBPOLBAPEX1HTT
SCHEMBL29025732 0.84 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL27689363 0.84 TSHR (0.44) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28127850 0.83 TSHR (0.41) TSHRTHRBPOLBAPEX1HTT
SCHEMBL31414736 0.82 TSHR (0.56) TSHRTHRBALDH1A1
SCHEMBL28311106 0.82 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28556164 0.81 NAAA (0.42) HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117209773-A Modified silicone oil, fluorescent heat-conducting silicone grease and preparation method and application thereof 广州集泰化工股份有限公司 2023-12-12 CN claimed
CN-1965377-A Anti-corrosion additive for electrical cable restoration fluids DOW CORNING (US) 2007-05-16 CN claimed
US-12624196-B2 Rubber composition, vulcanized object obtained from said rubber composition, and vulcanized molded object obtained from said rubber composition DENKA COMPANY LIMITED (JP) 2026-05-12 US disclosed
CN-119684682-A Heat-conducting silica gel gasket and preparation method and application thereof 广州集泰化工股份有限公司 2025-03-25 CN disclosed
CN-116285366-B Double-component heat-conducting gel and preparation method and application thereof 广州集泰化工股份有限公司 2025-03-25 CN disclosed
EP-4253466-B1 RUBBER COMPOSITION, VULCANIZED OBJECT OBTAINED FROM SAID RUBBER COMPOSITION, AND VULCANIZED MOLDED OBJECT OBTAINED FROM SAID RUBBER COMPOSITION DENKA COMPANY LTD (JP) 2024-10-02 EP disclosed
CN-112040936-B Transdermal therapeutic system for transdermal administration of solifenacin 罗曼治疗系统股份公司 2024-07-23 CN disclosed
CN-112175565-B Moisture-curable resin composition and cured product 三键有限公司 2024-07-02 CN disclosed
CN-111447926-B Transdermal therapeutic system for transdermal administration of guanfacine comprising at least one additive 罗曼治疗系统股份公司 2024-04-30 CN disclosed
CN-117897144-A Transdermal therapeutic system for transdermal administration of guanfacine comprising guanfacine and a monocarboxylic acid LTS罗曼治疗系统股份公司 2024-04-16 CN disclosed
CN-117858758-A Core-shell particles with organic polymer cores 沃特世科技公司 2024-04-09 CN disclosed
EP-1247644-A2 Support for lithographic printing plate and original forme for lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2002-10-09 EP disclosed
US-6447979-B1 Image recording body KONICA CORPORATION (JP) 2002-09-10 US disclosed
US-20020039702-A1 Writable by infrared laser beam exposure; support formed with an anodic oxidation coating having a predetermined density and/or vacancy ratio on a roughened surface of an aluminum substrate. FUJIFILM CORPORATION (JP) 2002-04-04 US disclosed
US-20020039703-A1 Preparation method for lithographic printing plate FUJIFILM CORPORATION (JP) 2002-04-04 US disclosed
EP-1170149-A2 Preparation method for lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2002-01-09 EP disclosed
US-20010041305-A1 Multilayer; aluminum substarte, photosensitive layer, polymer overcoating FUJIFILM CORPORATION (JP) 2001-11-15 US disclosed
EP-1142708-A1 Planographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2001-10-10 EP disclosed
CN-1314254-A Lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 2001-09-26 CN disclosed
EP-1106381-A1 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-06-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624196-B2 Rubber composition, vulcanized object obtained from said rubber composition, and vulcanized molded object obtained from said rubber composition ALG3, VCL, DNMT1 TSHR 4144/4885THRB 3181/4885POLB 1057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.