Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.55 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8749077 | 0.83 | TDP1 (0.42) | BAZ2BBAZ2AGAACYP1A2 | |
| SCHEMBL8103043 | 0.79 | BAZ2B (0.53) | BAZ2BBAZ2AALDH1A1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL653318 | 0.77 | BAZ2B (0.51) | BAZ2BBAZ2AALDH1A1GAAKMT2A | |
| SCHEMBL15318252 | 0.76 | BAZ2B (0.50) | BAZ2BBAZ2AALDH1A1GAALMNA | |
| SCHEMBL4544349 | 0.75 | BAZ2B (0.62) | BAZ2BBAZ2AALDH1A1GAAKMT2A | |
| SCHEMBL9908199 | 0.75 | BAZ2B (0.57) | BAZ2BBAZ2AALDH1A1GAAKMT2A | |
| SCHEMBL1298467 | 0.73 | BAZ2B (0.54) | BAZ2BBAZ2AALDH1A1GAAKMT2A | |
| SCHEMBL29191043 | 0.72 | BAZ2B (0.77) | BAZ2BBAZ2AALDH1A1GAAKMT2A | |
| SCHEMBL25815377 | 0.71 | BAZ2B (1.00) | BAZ2BBAZ2AALDH1A1GAAKMT2A | |
| SCHEMBL9285452 | 0.71 | BAZ2B (0.53) | BAZ2BBAZ2AALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051243-A | USEFUL IN THE TOPICAL AND SYSTEMIC TREATMENT OF DERMATOLOGICAL CONDITIONS ASSOCIATED WITH A KERATINIZATION DISORDER, DERMATOLOGICAL CONDITIONS (AND THE LIKE) INCLUDING AN INFLAMMATORY AND/OR IMMUNOALLERGIC COMPONENT | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2000-04-18 | — | — | US | disclosed |
| US-5709867-A | TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR, AND OPHTHALMOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-01-20 | — | — | US | disclosed |