Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.53 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL653318 | 0.98 | BAZ2B (0.51) | BAZ2BBAZ2AALDH1A1CYP1A2GAA | |
| SCHEMBL15318252 | 0.81 | BAZ2B (0.50) | BAZ2BBAZ2AALDH1A1CYP1A2GAA | |
| SCHEMBL5063281 | 0.80 | TDP1 (0.43) | ALDH1A1GAALMNACREBBP | |
| SCHEMBL8102674 | 0.79 | BAZ2B (0.55) | BAZ2BBAZ2AALDH1A1CYP1A2GAA | |
| SCHEMBL370477 | 0.78 | BAZ2B (0.54) | BAZ2BBAZ2AALDH1A1CYP1A2GAA | |
| SCHEMBL18236158 | 0.78 | CREBBP (0.61) | ALDH1A1GAAKMT2ACREBBP | |
| SCHEMBL21712949 | 0.77 | BAZ2B (0.53) | BAZ2BBAZ2AALDH1A1CYP1A2GAA | |
| SCHEMBL70354 | 0.76 | BAZ2B (0.71) | BAZ2BBAZ2AALDH1A1CYP1A2GAA | |
| SCHEMBL21060866 | 0.76 | BAZ2B (0.56) | BAZ2BBAZ2AALDH1A1CYP1A2GAA | |
| SCHEMBL162449 | 0.76 | BAZ2B (0.56) | BAZ2BBAZ2AALDH1A1CYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051243-A | USEFUL IN THE TOPICAL AND SYSTEMIC TREATMENT OF DERMATOLOGICAL CONDITIONS ASSOCIATED WITH A KERATINIZATION DISORDER, DERMATOLOGICAL CONDITIONS (AND THE LIKE) INCLUDING AN INFLAMMATORY AND/OR IMMUNOALLERGIC COMPONENT | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2000-04-18 | — | — | US | disclosed |
| US-5709867-A | TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR, AND OPHTHALMOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-01-20 | — | — | US | disclosed |