Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 1.00 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.69 |
| ▸ | BRD4 | O60885 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29191043 | 0.87 | BAZ2B (0.77) | BAZ2BBAZ2AALDH1A1BRD4GAA | |
| SCHEMBL14150292 | 0.85 | BAZ2B (0.73) | BAZ2BBAZ2AALDH1A1BRD4GAA | |
| SCHEMBL70354 | 0.83 | BAZ2B (0.71) | BAZ2BBAZ2AALDH1A1BRD4GAA | |
| SCHEMBL9147964 | 0.82 | BAZ2B (0.68) | BAZ2BBAZ2AALDH1A1BRD4GAA | |
| SCHEMBL9151585 | 0.82 | BAZ2B (0.68) | BAZ2BBAZ2AALDH1A1BRD4GAA | |
| SCHEMBL7965196 | 0.82 | BAZ2B (0.68) | BAZ2BBAZ2AALDH1A1BRD4GAA | |
| SCHEMBL26015021 | 0.81 | BAZ2B (0.69) | BAZ2BBAZ2AALDH1A1BRD4GAA | |
| SCHEMBL1664710 | 0.80 | BAZ2B (0.67) | BAZ2BBAZ2AALDH1A1BRD4GAA | |
| SCHEMBL4544324 | 0.80 | BAZ2B (0.67) | BAZ2BBAZ2AALDH1A1BRD4GAA | |
| SCHEMBL2221019 | 0.80 | TDP1 (0.67) | BAZ2BBAZ2AALDH1A1BRD4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117886734-A | Heterocyclic amide compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-04-16 | — | — | CN | disclosed |
| US-20230183248-A1 | PYRROLO[1,2-D][1,2,4]TRIAZINE-2-YL-ACETAMIDES AS INHIBITORS OF THE NLRP3 INFLAMMASOME PATHWAY | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-15 | — | — | US | disclosed |
| US-20230183248-A1 | PYRROLO[1,2-D][1,2,4]TRIAZINE-2-YL-ACETAMIDES AS INHIBITORS OF THE NLRP3 INFLAMMASOME PATHWAY | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183248-A1 | PYRROLO[1,2-D][1,2,4]TRIAZINE-2-YL-ACETAMIDES AS INHIBITORS OF THE NLRP3 INFLAMMASOME PATHWAY | NLRP3, NLRP1, IL1B | BAZ2B 295/4885BAZ2A 256/4885ALDH1A1 898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.