SCHEMBL8102701

SCHEMBL8102701

CCCCCCNc1ccccc1NCC

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.50
CHRM2 P08172 1/20 0.46
S1PR2 O95136 1/20 0.45
LMNA P02545 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
CNR2 P34972 4/20 0.45
KCNH3 Q9ULD8 1/20 0.45
NAAA Q02083 1/20 0.43
SIGMAR1 Q99720 1/20 0.43
TLR8 Q9NR97 1/20 0.42
CNR1 P21554 1/20 0.42
SOAT1 P35610 2/20 0.42
HTT P42858 2/20 0.42
MAPT P10636 1/20 0.42
ALDH1A1 P00352 1/20 0.41
EPHX1 P07099 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8535750 0.94 L3MBTL1 (0.54) L3MBTL1CHRM2S1PR2LMNASMN1; SMN2
SCHEMBL30174089 0.94 L3MBTL1 (0.54) L3MBTL1CHRM2S1PR2LMNASMN1; SMN2
SCHEMBL11266453 0.94 L3MBTL1 (0.54) L3MBTL1CHRM2S1PR2LMNASMN1; SMN2
SCHEMBL11266466 0.94 L3MBTL1 (0.54) L3MBTL1CHRM2S1PR2LMNASMN1; SMN2
SCHEMBL1724131 0.92 L3MBTL1 (0.51) L3MBTL1CHRM2S1PR2LMNASMN1; SMN2
SCHEMBL9011307 0.86 L3MBTL1 (0.49) L3MBTL1CHRM2S1PR2LMNASMN1; SMN2
SCHEMBL309485 0.85 TLR8 (0.53) L3MBTL1CHRM2SMN1; SMN2NPSR1KCNH3
SCHEMBL24846615 0.84 L3MBTL1 (0.47) L3MBTL1CHRM2S1PR2LMNASMN1; SMN2
SCHEMBL25229719 0.82 HTT (0.67) L3MBTL1CHRM2S1PR2LMNASMN1; SMN2
SCHEMBL3682496 0.82 HTT (0.67) L3MBTL1CHRM2S1PR2LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6037473-A AS SUNSCREENS IN COSMETIC AND PHARMACEUTICAL PREPARATIONS; FOR ENHANCING PHOTOSTABILITY OF INDUSTRIAL PRODUCTS SUCH AS PAINTS, VARNISHES, PLASTICS, TEXTILES, PACKAGING MATERIALS AND RUBBERS HAARMANN & REIMER GMBH (DE) 2000-03-14 US disclosed
US-5961960-A Use of substituted benzazoles as UV absorbers, new benzazoles and processes for their preparation HAARMANN & REIMER GMBH (DE) 1999-10-05 US disclosed