Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7036035 | 0.86 | KDM4E (0.54) | TP53SMN1; SMN2GAAKDM4EALDH1A1 | |
| SCHEMBL10005374 | 0.81 | TLR8 (0.71) | TP53SMN1; SMN2GAAKDM4EALDH1A1 | |
| SCHEMBL229426 | 0.78 | TP53 (0.68) | TP53SMN1; SMN2GAAKDM4EALDH1A1 | |
| SCHEMBL19229532 | 0.77 | DRD2 (0.76) | TP53SMN1; SMN2GAAKDM4EALDH1A1 | |
| SCHEMBL30496676 | 0.76 | KDM4E (1.00) | TP53SMN1; SMN2GAAKDM4EALDH1A1 | |
| SCHEMBL6142493 | 0.76 | TP53 (0.65) | TP53SMN1; SMN2GAAKDM4EALDH1A1 | |
| SCHEMBL28480003 | 0.76 | BRD4 (0.57) | TP53SMN1; SMN2GAAKDM4EALDH1A1 | |
| SCHEMBL13270259 | 0.75 | KDM4E (0.50) | TP53SMN1; SMN2GAAKDM4EALDH1A1 | |
| SCHEMBL18085346 | 0.75 | TP53 (0.67) | TP53SMN1; SMN2GAAALDH1A1NPSR1 | |
| SCHEMBL29412148 | 0.74 | MAPT (0.53) | TP53SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6037473-A | AS SUNSCREENS IN COSMETIC AND PHARMACEUTICAL PREPARATIONS; FOR ENHANCING PHOTOSTABILITY OF INDUSTRIAL PRODUCTS SUCH AS PAINTS, VARNISHES, PLASTICS, TEXTILES, PACKAGING MATERIALS AND RUBBERS | HAARMANN & REIMER GMBH (DE) | 2000-03-14 | — | — | US | disclosed |
| US-5961960-A | Use of substituted benzazoles as UV absorbers, new benzazoles and processes for their preparation | HAARMANN & REIMER GMBH (DE) | 1999-10-05 | — | — | US | disclosed |
| EP-0843995-A2 | Use of substituted benzazoles as UV absorbents, new benzazoles and their preparation | HAARMANN & REIMER GMBH (DE) | 1998-05-27 | — | — | EP | disclosed |