Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | TP53 | P04637 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8102717 | 0.86 | TP53 (0.64) | KDM4EALDH1A1LMNAGAATSHR | |
| SCHEMBL28480003 | 0.75 | BRD4 (0.57) | KDM4EALDH1A1LMNAGAATSHR | |
| SCHEMBL927859 | 0.72 | HTT (0.44) | KDM4EALDH1A1LMNAGAATSHR | |
| SCHEMBL29412041 | 0.72 | KDM4E (0.56) | KDM4EALDH1A1LMNAGAATSHR | |
| SCHEMBL29411941 | 0.72 | BRD4 (0.52) | KDM4EALDH1A1LMNAGAATSHR | |
| SCHEMBL29411945 | 0.72 | ALDH1A1 (0.53) | KDM4EALDH1A1LMNAGAATSHR | |
| SCHEMBL29979980 | 0.72 | HTT (0.43) | KDM4EALDH1A1LMNAGAATSHR | |
| SCHEMBL1020149 | 0.72 | HTT (0.43) | KDM4EALDH1A1LMNAGAATSHR | |
| SCHEMBL29411955 | 0.71 | TP53 (0.54) | KDM4EALDH1A1LMNAGAATSHR | |
| SCHEMBL10005374 | 0.71 | TLR8 (0.71) | KDM4EALDH1A1LMNAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028120-B1 | Organosilicon compounds with N-substituted benzimidazole-benzazole or benzofuranyl-benzazole groups, sunscreen compositions containing these compounds and their use | OREAL (FR) | 2003-03-19 | — | — | EP | disclosed |