⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5017147 | 0.79 | — | — | |
| SCHEMBL2220182 | 0.79 | — | — | |
| SCHEMBL9429526 | 0.75 | — | — | |
| SCHEMBL8780769 | 0.69 | — | — | |
| SCHEMBL11478254 | 0.68 | POLB (0.32) | — | |
| SCHEMBL29775906 | 0.68 | — | — | |
| SCHEMBL28773722 | 0.65 | — | — | |
| SCHEMBL17484864 | 0.63 | — | — | |
| SCHEMBL5023745 | 0.61 | — | — | |
| SCHEMBL27872648 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674626-B1 | SELECTIVE AROMATASE INHIBITING COMPOUNDS | RISTO ARVO SAKARI LAMMINTAUSTA (FI) | 2000-07-19 | — | — | EP | disclosed |
| US-5962495-A | ESTROGEN SENSITIVE DISEASES; BREAST CANCER; PROSTATE TUMORS | RISTO ARVO SAKARI LAMMINTAUSTA (FI) | 1999-10-05 | — | — | US | disclosed |
| US-5703109-A | CYANOPHENYL-1,2,4-TRIAZOLE DERIVATIVE | Oy, Orion-yhtyma (FI) | 1997-12-30 | — | — | US | disclosed |
| EP-0674626-A1 | NOVEL SELECTIVE AROMATASE INHIBITING COMPOUNDS | ORION-YHTYMÄ OY (FI) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994013645-A1 | NOVEL SELECTIVE AROMATASE INHIBITING COMPOUNDS | Orion-Yhtymä Oy (FI) | 1994-06-23 | — | — | WO | disclosed |