Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103143 | 0.75 | ALDH1A1 (0.49) | ALDH1A1RAB9ANPC1TSHRLMNA | |
| SCHEMBL9536661 | 0.68 | ALDH1A1 (0.44) | ALDH1A1RAB9ANPC1TSHRLMNA | |
| SCHEMBL8111879 | 0.67 | MAPT (0.43) | ALDH1A1RAB9ANPC1TSHRLMNA | |
| SCHEMBL17668058 | 0.64 | PKM (0.46) | ALDH1A1RAB9ANPC1TSHRLMNA | |
| SCHEMBL9642664 | 0.63 | ALDH1A1 (0.53) | ALDH1A1RAB9ANPC1TSHRLMNA | |
| SCHEMBL9642141 | 0.63 | ALDH1A1 (0.50) | ALDH1A1RAB9ANPC1TSHRLMNA | |
| SCHEMBL4212033 | 0.63 | ALDH1A1 (0.70) | ALDH1A1RAB9ANPC1TSHRKDM4E | |
| SCHEMBL9642193 | 0.63 | ALDH1A1 (0.47) | ALDH1A1RAB9ANPC1TSHRKDM4E | |
| SCHEMBL8111887 | 0.63 | ALDH1A1 (0.49) | ALDH1A1RAB9ANPC1TSHRLMNA | |
| SCHEMBL9640970 | 0.63 | ALDH1A1 (0.49) | ALDH1A1RAB9ANPC1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0678094-B1 | 2-ALKOXY-4-HYDRAZINOPYRIMIDINE COMPOUNDS AND THEIR USE IN THE PREPARATION OF 5-ALKOXY[1,2,4]TRIAZOLO[4,3-C]PYRIMIDINE-3(2H)-THIONE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2000-05-03 | — | — | EP | disclosed |
| EP-0678093-B1 | 5-ALKOXY-1,2,4-TRIAZOLO[4,3-C]PYRIMIDINE-3(2H)-THIONE COMPOUNDS AND THEIR USE IN THE PREPARATION OF 5-ALKOXY-1,2,4-TRIAZOLO[1,5-C]PYRIMIDINE-2(3H)-THIONE AND 3-HYDROCARBYLTHIO-5-ALKOXY-1,2,4-TRIAZOLO[4,3-C]PYRIMIDINE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2000-01-05 | — | — | EP | disclosed |
| US-5563269-A | 2-alkoxy-4-hydrazinopyrimidine compounds and their use in the preparation of 5-alkoxy-1,2,4-triazolo(4,3-C)-pyrimidine-3 (2H)-thione compounds | DOWELANCO (US) | 1996-10-08 | — | — | US | disclosed |
| US-5480991-A | 2-Alkoxy-4-hydroazinopyrimidine compounds and their use in the preparation of 5-alkoxy-1,2,4-triazolo[4,3-c]pyrimidine-3(2H)-thione compounds | DOWELANCO (US) | 1996-01-02 | — | — | US | disclosed |
| US-5461153-A | 2-alkoxy-4-hydrazinopyrimidine compounds | DOWELANCO (US) | 1995-10-24 | — | — | US | disclosed |