Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL10432593 | 0.94 | TSHR (0.37) | TSHRTHRBOPRM1ALDH1A1LMNA | |
| Hexane SCHEMBL10991526 | 0.87 | TSHR (0.47) | TSHRTHRBOPRM1ALDH1A1LMNA | |
| Ether SCHEMBL2837591 | 0.87 | ALDH1A1 (0.37) | THRBALDH1A1LMNA | |
| Ether SCHEMBL3794585 | 0.87 | ALDH1A1 (0.37) | THRBALDH1A1LMNA | |
| Ether SCHEMBL3701280 | 0.87 | ALDH1A1 (0.37) | THRBALDH1A1LMNA | |
| Ether SCHEMBL96502 | 0.87 | — | — | |
| Ether SCHEMBL8089271 | 0.87 | ALDH1A1 (0.37) | THRBALDH1A1LMNA | |
| Hexane SCHEMBL4268972 | 0.87 | TSHR (0.54) | TSHRTHRBOPRM1ALDH1A1LMNA | |
| Hexane SCHEMBL14814561 | 0.87 | TSHR (0.54) | TSHRTHRBOPRM1ALDH1A1LMNA | |
| Hexane SCHEMBL7917492 | 0.87 | TSHR (0.54) | TSHRTHRBOPRM1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0482208-B1 | PYRIDAZINONE DERIVATIVE | NISSAN CHEMICAL IND LTD (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5318968-A | Antithrombotic agents; cardiotonic agents; vasodilators | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1994-06-07 | — | — | US | disclosed |
| US-5314883-A | Vasodilation, anticoagulants | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1994-05-24 | — | — | US | disclosed |
| US-5202323-A | Antithrombotic, inotropic, vasodilator, antiallergen | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0482208-A1 | PYRIDAZINONE DERIVATIVE | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-04-29 | — | — | EP | disclosed |