⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11834983 | 0.82 | CA2 (0.35) | — | |
| SCHEMBL9413595 | 0.79 | — | — | |
| SCHEMBL11849276 | 0.78 | PRKD3 (0.33) | — | |
| SCHEMBL31682148 | 0.76 | CA2 (0.32) | — | |
| SCHEMBL2819836 | 0.74 | TSHR (0.35) | — | |
| SCHEMBL7155573 | 0.74 | SMPD1 (0.37) | — | |
| SCHEMBL2819835 | 0.74 | TSHR (0.35) | — | |
| SCHEMBL10976354 | 0.73 | — | — | |
| SCHEMBL10976357 | 0.73 | — | — | |
| SCHEMBL17442138 | 0.71 | OPRM1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643063-B1 | Process for preparing a higher cuprate complex | SEARLE & CO (US) | 2000-01-26 | — | — | EP | disclosed |
| EP-0452843-B1 | Process for preparing prostaglandin analogs using organozirconium compounds | SEARLE & CO (US) | 1995-06-14 | — | — | EP | disclosed |
| EP-0643063-A2 | Process for preparing a higher cuprate complex | G.D. Searle & Co. (US) | 1995-03-15 | — | — | EP | disclosed |
| US-5252763-A | Higher order cuprate complexes from alkyne, zirconocene chloride hydride, alkyllithium and cuprous cyanide | G. D. SEARLE & CO. (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0452843-A2 | Process for preparing prostaglandin analogs using organozirconium compounds | G.D. Searle & Co. (US) | 1991-10-23 | — | — | EP | disclosed |
| US-4730065-A | BRONCHODILATORS, HYPOTENSIVES, ANTISECRETORY | AMERICAN CYANAMID COMPANY (US) | 1988-03-08 | — | — | US | disclosed |
| US-4518790-A | 15-Deoxy-16-hydroxy-16-vinyl and cyclopropyl substituted prostanoic acids and congeners | AMERICAN CYANAMID COMPANY (US) | 1985-05-21 | — | — | US | disclosed |
| US-4504417-A | 15-Deoxy-16-hydroxy-16-substituted prostanoic acids and congeners | AMERICAN CYANAMID COMPANY (US) | 1985-03-12 | — | — | US | disclosed |
| US-4429148-A | PROSTAGLANDINS; BRONCHODILATORS, HYPTOTENSIVES | AMERICAN CYANAMID COMPANY (US) | 1984-01-31 | — | — | US | disclosed |
| US-4358605-A | BRONCHODILATORS, HYPOTENSIVE, ANTIULCER | AMERICAN CYANAMID COMPANY (US) | 1982-11-09 | — | — | US | disclosed |
| US-4189597-A | PROSTAGLANDINS, BRONCHODILATORS | AMERICAN CYANAMID COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
| US-4172839-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1979-10-30 | — | — | US | disclosed |
| US-4170597-A | 1-Hydroxymethyl-1-oxo-prostane derivatives of the E2 series | AMERICAN CYANAMID COMPANY (US) | 1979-10-09 | — | — | US | disclosed |
| US-4165331-A | PROSTAGLANDINS/AND DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1979-08-21 | — | — | US | disclosed |
| EP-0002590-A1 | Novel prostaglandin compounds, processes for the preparation thereof and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-06-27 | — | — | EP | disclosed |
| US-4154959-A | 11-(2-Hydroxyethylthio)prostenoic acid E series derivatives | AMERICAN CYANAMID COMPANY (US) | 1979-05-15 | — | — | US | disclosed |
| US-4154954-A | BRONCHODILATOR AGENTS; ANTIINFLAMMATORY AGENTS | AMERICAN CYANAMID COMPANY (US) | 1979-05-15 | — | — | US | disclosed |
| US-4131737-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1978-12-26 | — | — | US | disclosed |
| US-4085272-A | BRONCHODILATORS, INFLAMMATORY MEDEATOR RELEASE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1978-04-18 | — | — | US | disclosed |
| US-4061670-A | BRONCHODILATOR, HYPOTENSIVE, ANTISECRETORY | AMERICAN CYANAMID COMPANY (US) | 1977-12-06 | — | — | US | disclosed |