Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357256 | 1.00 | MEN1 (0.38) | MEN1KMT2AGRIA1GRIA2GRIA3 | |
| SCHEMBL4367402 | 0.91 | MAPK14 (0.35) | MEN1KMT2ATP53LRRK2MAPK14 | |
| SCHEMBL4375379 | 0.89 | GRIA1 (0.38) | GRIA1GRIA2GRIA3GRIA4MCHR1 | |
| SCHEMBL4375384 | 0.89 | GRIA1 (0.38) | GRIA1GRIA2GRIA3GRIA4MCHR1 | |
| SCHEMBL13592447 | 0.89 | GRIA1 (0.38) | GRIA1GRIA2GRIA3GRIA4GAA | |
| SCHEMBL13592439 | 0.89 | GRIA1 (0.38) | GRIA1GRIA2GRIA3GRIA4GAA | |
| SCHEMBL4373619 | 0.89 | GRIA1 (0.37) | MEN1KMT2AGRIA1GRIA2GRIA3 | |
| SCHEMBL4373620 | 0.89 | GRIA1 (0.37) | MEN1KMT2AGRIA1GRIA2GRIA3 | |
| SCHEMBL14287073 | 0.89 | PGR (0.37) | MEN1KMT2AGRIA1GRIA2GRIA3 | |
| SCHEMBL14287096 | 0.89 | ALOX15 (0.40) | MEN1KMT2AMAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781284-B1 | INDOLE-2,3-DIONE-3-OXIME DERIVATIVES, THEIR PREPARATION AND USE | NEUROSEARCH AS (DK) | 2000-01-12 | — | — | EP | disclosed |
| EP-0698025-B1 | AMPA ANTAGONISTS AND A METHOD OF TREATMENT THEREWITH | NEUROSEARCH AS (DK) | 1997-12-17 | — | — | EP | disclosed |