Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
| ▸ | CHUK | O15111 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | NPY2R | P49146 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8110894 | 0.89 | HTR6 (0.36) | HTR6GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8140548 | 0.86 | HTR6 (0.40) | HTR6GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6607625 | 0.86 | HTR6 (0.37) | HTR6GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8133111 | 0.85 | HTR6 (0.42) | HTR6GRIA1GRIA2GRIA3GRIA4 | |
| Hydrochloric Acid SCHEMBL6609047 | 0.85 | HTR6 (0.37) | HTR6GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6607933 | 0.83 | HTR6 (0.38) | HTR6GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL4401527 | 0.83 | HTR6 (0.43) | HTR6GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8133241 | 0.83 | HTR6 (0.43) | HTR6GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL4393716 | 0.83 | HTR6 (0.43) | HTR6GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6607562 | 0.83 | HTR6 (0.39) | HTR6GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781284-B1 | INDOLE-2,3-DIONE-3-OXIME DERIVATIVES, THEIR PREPARATION AND USE | NEUROSEARCH AS (DK) | 2000-01-12 | — | — | EP | claimed |