Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10863883 | 0.82 | — | — | |
| SCHEMBL7587103 | 0.81 | SLC6A1 (0.33) | — | |
| SCHEMBL2905562 | 0.81 | SLC6A1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL7590833 | 0.79 | SLC6A1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL8112201 | 0.79 | SLC6A1 (0.32) | — | |
| SCHEMBL1351693 | 0.79 | CHRM2 (0.33) | — | |
| SCHEMBL31031091 | 0.78 | CHRM2 (0.33) | — | |
| SCHEMBL19209920 | 0.78 | SLC6A1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL28060494 | 0.78 | CHRM2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL27835399 | 0.78 | CHRM2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483608-A | Arenobufagin derivative and preparation method thereof, the composition comprising the derivative, and application thereof | SHANGHAI INST MATERIA MEDICA CAS | 2019-11-22 | — | — | CN | disclosed |
| EP-0756593-B1 | PROCESS FOR PREPARING 2-PIPERAZINE CARBOXYLIC ACID DERIVATIVES | LONZA AG (CH) | 2000-09-20 | — | — | EP | disclosed |
| EP-0756593-B1 | PROCESS FOR PREPARING 2-PIPERAZINE CARBOXYLIC ACID DERIVATIVES | LONZA AG (CH) | 2000-09-20 | — | — | EP | disclosed |
| EP-0756593-A1 | PROCESS FOR PREPARING 2-PIPERAZINE CARBOXYLIC ACID DERIVATIVES | LONZA AG (CH) | 1997-02-05 | — | — | EP | disclosed |
| EP-0756593-A1 | PROCESS FOR PREPARING 2-PIPERAZINE CARBOXYLIC ACID DERIVATIVES | LONZA AG (CH) | 1997-02-05 | — | — | EP | disclosed |
| WO-1995029169-A3 | PROCESS FOR PREPARING 2-PIPERAZINE CARBOXYLIC ACID DERIVATIVES | LONZA AG (CH) | 1995-12-21 | — | — | WO | disclosed |
| WO-1995029169-A2 | PROCESS FOR PREPARING 2-PIPERAZINE CARBOXYLIC ACID DERIVATIVES | LONZA AG (CH) | 1995-11-02 | — | — | WO | disclosed |
| WO-1995029169-A2 | PROCESS FOR PREPARING 2-PIPERAZINE CARBOXYLIC ACID DERIVATIVES | LONZA AG (CH) | 1995-11-02 | — | — | WO | disclosed |