Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14954188 | 0.94 | CTSD (0.33) | CTSD | |
| Iodide SCHEMBL810379 | 0.94 | CTSD (0.33) | CTSD | |
| Fluoride Ion SCHEMBL14954084 | 0.94 | CTSD (0.33) | CTSD | |
| Bromide SCHEMBL809753 | 0.94 | CTSD (0.33) | CTSD | |
| SCHEMBL2230540 | 0.73 | CTSD (0.43) | CTSD | |
| Hydrochloric Acid SCHEMBL8069109 | 0.71 | CTSD (0.33) | CTSD | |
| Hydrochloric Acid SCHEMBL1971876 | 0.71 | CTSD (0.33) | CTSD | |
| SCHEMBL198310 | 0.67 | CTSD (0.35) | CTSD | |
| Hydrochloric Acid SCHEMBL7869576 | 0.67 | CTSD (0.35) | CTSD | |
| SCHEMBL4652458 | 0.67 | CTSD (0.35) | CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115947756-A | Method for synthesizing polyfluoroalkyl aryl ether by directly coupling aryl halide and polyfluoroalkyl alcohol | 西湖大学 | 2023-04-11 | — | — | CN | claimed |
| CN-115850153-A | Preparation method of adjustable isoindole compound | 广东工业大学 | 2023-03-28 | — | — | CN | claimed |
| CN-115710249-A | Preparation method of polysubstituted isoquinoline and 1, 6-naphthyridine compound and common molecular framework of photoelectric material | 广东工业大学 | 2023-02-24 | — | — | CN | claimed |
| CN-115353510-A | Preparation method and application of isoindole compound | 广东工业大学 | 2022-11-18 | — | — | CN | claimed |
| CN-115160211-A | Green synthesis method of isoindolinone compounds | 温州大学 | 2022-10-11 | — | — | CN | claimed |
| CN-115108960-A | Preparation method and application of polysubstituted indole compound | 广东工业大学 | 2022-09-27 | — | — | CN | claimed |
| CN-115057808-A | Synthetic method of Z-3-vinyl substituted isoindolinone compound | 温州大学 | 2022-09-16 | — | — | CN | claimed |
| CN-112939753-B | Synthesis method of 1-indanone compound | 浙江大学 | 2022-04-05 | — | — | CN | claimed |
| CN-112939780-B | Synthetic method of indanone derivatives | 浙江大学 | 2022-04-05 | — | — | CN | claimed |
| CN-110218172-B | Method for preparing N-aryl sulfonamide from indoline and aryl sulfonamide | 常州大学 | 2022-03-22 | — | — | CN | claimed |
| CN-112939753-A | Synthesis method of 1-indanone compound | 浙江大学 | 2021-06-11 | — | — | CN | claimed |
| CN-112939780-A | Synthetic method of indanone derivatives | 浙江大学 | 2021-06-11 | — | — | CN | claimed |
| CN-107892694-B | Preparation method of pyrazolidinone compound containing bridged ring structure | 河南师范大学 | 2020-03-20 | — | — | CN | claimed |
| US-12622909-B2 | Allosteric EGFR inhibitors and methods of use thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2026-05-12 | — | — | US | disclosed |
| EP-4192454-B1 | AZABICYCLO-AMINO-TRIAZINE COMPOUNDS FOR MODULATING SPLICING FOR THE TREATMENT OF NEUROLOGICAL DISEASES | SKYHAWK THERAPEUTICS INC (US) | 2026-04-22 | — | — | EP | disclosed |
| EP-4716531-A2 | HETEROCYCLIC COMPOUNDS AS NRAS INHIBITORS | Board of Regents, The University of Texas System (US) | 2026-04-01 | — | — | EP | disclosed |
| EP-1741693-B1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE ALCOHOLS | NAGOYA IND SCIENCE RES INST (JP) | 2011-08-03 | — | — | EP | disclosed |
| EP-1741693-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE ALCOHOLS | Nagoya Industrial Science Research Institute (JP) | 2007-01-10 | — | — | EP | disclosed |
| EP-0971865-A1 | TRANSFER HYDROGENATION PROCESS AND CATALYST | Avecia Limited (GB) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998042643-A1 | TRANSFER HYDROGENATION PROCESS AND CATALYST | AVECIA LIMITED (GB) | 1998-10-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12622909-B2 | Allosteric EGFR inhibitors and methods of use thereof | EGFR, ERBB3, ERBB2 | CTSD 3476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.