Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531691 | 1.00 | MAOA (0.34) | MAOAMAOBAADATMEN1KMT2A | |
| SCHEMBL17928994 | 1.00 | MAOA (0.34) | MAOAMAOBAADATMEN1KMT2A | |
| SCHEMBL17928996 | 1.00 | MAOA (0.34) | MAOAMAOBAADATMEN1KMT2A | |
| SCHEMBL8531689 | 1.00 | MAOA (0.34) | MAOAMAOBAADATMEN1KMT2A | |
| SCHEMBL8050352 | 1.00 | MAOA (0.34) | MAOAMAOBAADATMEN1KMT2A | |
| SCHEMBL18080870 | 0.84 | MAOA (0.37) | MAOAMAOBAADATMEN1KMT2A | |
| SCHEMBL9113014 | 0.81 | MAOA (0.39) | MAOAMAOBMEN1KMT2AGAA | |
| SCHEMBL15630882 | 0.70 | MEN1 (0.36) | MAOAMAOBAADATMEN1KMT2A | |
| SCHEMBL8692639 | 0.70 | MAOA (0.39) | MAOAMAOBMEN1KMT2AGAA | |
| SCHEMBL7293415 | 0.70 | MEN1 (0.36) | MAOAMAOBAADATMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6165777-A | Process for the resolution of cis 1,2-indane diols using Pseudomonas putida | ZENECA LIMITED (GB) | 2000-12-26 | — | — | US | disclosed |