Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18080870 | 0.86 | MAOA (0.37) | MAOAMAOBMEN1GAAKMT2A | |
| SCHEMBL27788665 | 0.83 | MAOA (0.32) | MAOAMAOBFUCA1 | |
| SCHEMBL8531691 | 0.81 | MAOA (0.34) | MAOAMAOBMEN1GAAKMT2A | |
| SCHEMBL17928994 | 0.81 | MAOA (0.34) | MAOAMAOBMEN1GAAKMT2A | |
| SCHEMBL17928996 | 0.81 | MAOA (0.34) | MAOAMAOBMEN1GAAKMT2A | |
| SCHEMBL8103100 | 0.81 | MAOA (0.34) | MAOAMAOBMEN1GAAKMT2A | |
| SCHEMBL8531689 | 0.81 | MAOA (0.34) | MAOAMAOBMEN1GAAKMT2A | |
| SCHEMBL8050352 | 0.81 | MAOA (0.34) | MAOAMAOBMEN1GAAKMT2A | |
| SCHEMBL13397737 | 0.79 | HSP90AA1 (0.39) | MEN1KMT2APOLB | |
| SCHEMBL13417270 | 0.79 | HSP90AA1 (0.39) | MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |