Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 17/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103204 | 1.00 | GPR52 (0.55) | GPR52ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL11774828 | 0.86 | HDAC3 (0.47) | GPR52ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL11774835 | 0.86 | HDAC3 (0.47) | GPR52ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL9715286 | 0.85 | GPR52 (0.57) | GPR52ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL7762164 | 0.85 | GPR52 (0.57) | GPR52ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL7762166 | 0.85 | GPR52 (0.57) | GPR52ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL11772102 | 0.85 | TRPV1 (0.50) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL11772108 | 0.85 | TRPV1 (0.50) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL11775695 | 0.83 | TRPV1 (0.53) | MAOB | |
| SCHEMBL11773033 | 0.83 | TRPV1 (0.53) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2859002-B1 | SILICON-BASED CROSS COUPLING AGENTS AND METHODS OF THEIR USE | UNIV PENNSYLVANIA (US) | 2020-12-30 | — | — | EP | disclosed |
| US-9850261-B2 | Silicon-based cross coupling agents and methods of their use | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2017-12-26 | — | — | US | disclosed |
| US-9850261-B2 | Silicon-based cross coupling agents and methods of their use | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2017-12-26 | — | — | US | disclosed |
| US-20170210766-A1 | SILICON-BASED CROSS COUPLING AGENTS AND METHODS OF THEIR USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-07-27 | — | — | US | disclosed |
| US-20170210766-A1 | SILICON-BASED CROSS COUPLING AGENTS AND METHODS OF THEIR USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-07-27 | — | — | US | disclosed |
| US-9499660-B2 | Silicon-based cross coupling agents and methods of their use | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-11-22 | — | — | US | disclosed |
| US-9499660-B2 | Silicon-based cross coupling agents and methods of their use | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-11-22 | — | — | US | disclosed |
| WO-2016011231-A1 | SILICON-BASED CROSS COUPLING AGENTS AND METHODS OF THEIR USE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-01-21 | — | — | WO | disclosed |
| US-20150152216-A1 | SILICON-BASED CROSS COUPLING AGENTS AND METHODS OF THEIR USE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2015-06-04 | — | — | US | disclosed |
| US-20150152216-A1 | SILICON-BASED CROSS COUPLING AGENTS AND METHODS OF THEIR USE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2015-06-04 | — | — | US | disclosed |
| JP-2000044499-A | PRODUCTION OF HALOGENATED ALKENYL AND ALKENYL SILANE FROM ALDEHYDE | JAPAN SCIENCE & TECHNOLOGY CORP | 2000-02-15 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170210766-A1 | SILICON-BASED CROSS COUPLING AGENTS AND METHODS OF THEIR USE | RAD51, CA1, DCLRE1A | GPR52 4707/4885ALDH1A1 4497/4885HPGD 2119/4885 |
| US-20150152216-A1 | SILICON-BASED CROSS COUPLING AGENTS AND METHODS OF THEIR USE | RAD51, CA1, DCLRE1A | GPR52 4707/4885ALDH1A1 4497/4885HPGD 2119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.