Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I3 | Q14994 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.40 |
| ▸ | SHBG | P04278 | 2/20 | 0.40 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21340339 | 0.77 | LMNA (0.64) | LMNAGPBAR1SHBGSERPINA6CYP1A2 | |
| SCHEMBL8229897 | 0.70 | CDC25A (0.38) | — | |
| SCHEMBL8107009 | 0.70 | CDC25A (0.38) | — | |
| SCHEMBL27461585 | 0.70 | CDC25A (0.38) | — | |
| SCHEMBL7145450 | 0.70 | CDC25A (0.38) | — | |
| SCHEMBL22275647 | 0.66 | LMNA (0.50) | NR1I3LMNAGPBAR1SHBGSERPINA6 | |
| SCHEMBL10079366 | 0.66 | LMNA (0.50) | NR1I3LMNAGPBAR1SHBGSERPINA6 | |
| SCHEMBL15164640 | 0.66 | LMNA (0.46) | NR1I3LMNAGPBAR1SHBGSERPINA6 | |
| SCHEMBL17471293 | 0.63 | CNR2 (0.33) | TSHR | |
| SCHEMBL19253230 | 0.62 | NR1I3 (0.57) | NR1I3LMNAGPBAR1SHBGSERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771789-B1 | 1 alpha, 26-dihydroxy-D-homo-vitamin D3 | HOFFMANN LA ROCHE (CH) | 2000-02-16 | — | — | EP | disclosed |
| EP-0771789-A1 | 1 alpha, 26-dihydroxy-D-homo-vitamin D3 | F. HOFFMANN-LA ROCHE AG (CH) | 1997-05-07 | — | — | EP | disclosed |