Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7145450 | 1.00 | CDC25A (0.38) | CDC25ACDC25B | |
| SCHEMBL27461585 | 1.00 | CDC25A (0.38) | CDC25ACDC25B | |
| SCHEMBL8229897 | 1.00 | CDC25A (0.38) | CDC25ACDC25B | |
| SCHEMBL27501643 | 0.77 | — | — | |
| SCHEMBL7151331 | 0.77 | CHRM2 (0.33) | — | |
| SCHEMBL13317672 | 0.72 | CDC25A (0.42) | CDC25ACDC25B | |
| SCHEMBL8103202 | 0.70 | NR1I3 (0.40) | — | |
| SCHEMBL13298441 | 0.67 | CDC25A (0.40) | CDC25ACDC25B | |
| SCHEMBL27462429 | 0.67 | CDC25A (0.39) | CDC25ACDC25B | |
| SCHEMBL7144061 | 0.66 | CYP19A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153605-A | Arylsecocholadiene derivatives | HOFFMAN-LA ROCHE INC. (US) | 2000-11-28 | — | — | US | disclosed |
| EP-0771789-B1 | 1 alpha, 26-dihydroxy-D-homo-vitamin D3 | HOFFMANN LA ROCHE (CH) | 2000-02-16 | — | — | EP | disclosed |
| US-5905074-A | SKIN DISORDERS, ANTITUMOR AGENTS, VITAMIN D DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 1999-05-18 | — | — | US | disclosed |
| EP-0771789-A1 | 1 alpha, 26-dihydroxy-D-homo-vitamin D3 | F. HOFFMANN-LA ROCHE AG (CH) | 1997-05-07 | — | — | EP | disclosed |