Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096940 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDTSHRNPC1 | |
| SCHEMBL8097874 | 0.81 | MAPT (0.49) | ALDH1A1MAPTHPGDTSHRNPC1 | |
| SCHEMBL8090390 | 0.81 | ALDH1A1 (0.68) | ALDH1A1MAPTHPGDTSHRKDM4E | |
| SCHEMBL8097532 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL8096856 | 0.81 | TSHR (0.46) | ALDH1A1MAPTHPGDTSHRNPC1 | |
| SCHEMBL8098555 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL8089737 | 0.81 | PBRM1 (0.43) | ALDH1A1MAPTHPGDTSHRSMN1; SMN2 | |
| SCHEMBL8103664 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPTHPGDTSHRKDM4E | |
| SCHEMBL8089997 | 0.78 | DDB1 (0.49) | ALDH1A1MAPTHPGDTSHRNPC1 | |
| SCHEMBL8103668 | 0.78 | MAPT (0.46) | ALDH1A1MAPTHPGDTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |