Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089623 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDTSHRGAA | |
| SCHEMBL8103216 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL8097874 | 0.81 | MAPT (0.49) | ALDH1A1MAPTHPGDTSHRGAA | |
| SCHEMBL8096856 | 0.81 | TSHR (0.46) | ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL8090390 | 0.81 | ALDH1A1 (0.68) | ALDH1A1MAPTHPGDTSHRSLC6A2 | |
| SCHEMBL8089997 | 0.78 | DDB1 (0.49) | ALDH1A1MAPTHPGDTSHRGAA | |
| SCHEMBL8089737 | 0.78 | PBRM1 (0.43) | ALDH1A1MAPTHPGDTSHRMGLL | |
| SCHEMBL8099374 | 0.78 | ABCC9 (0.43) | ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL8103668 | 0.78 | MAPT (0.46) | ALDH1A1MAPTHPGDTSHRGAA | |
| SCHEMBL8098555 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |