Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL316378 | 0.88 | TSHR (0.48) | KMT2APOLBLMNAMDM2L3MBTL1 | |
| SCHEMBL7141971 | 0.86 | PTPN1 (0.64) | GSK3BPTPN1KMT2APOLBLMNA | |
| Methoxymethane SCHEMBL27516601 | 0.82 | GSK3B (0.83) | GSK3BPTPN1KMT2APOLBLMNA | |
| SCHEMBL28835358 | 0.79 | GSK3B (0.60) | GSK3BPTPN1KMT2APOLBLMNA | |
| Methyl Alcohol SCHEMBL7806962 | 0.78 | GSK3B (0.91) | GSK3BPTPN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL19331717 | 0.78 | GSK3B (1.00) | GSK3BPTPN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL18849535 | 0.78 | GSK3B (1.00) | GSK3BPTPN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL7621 | 0.78 | GSK3B (1.00) | GSK3BPTPN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL28135287 | 0.77 | GSK3B (0.61) | GSK3BPTPN1KMT2APOLBLMNA | |
| Hydrogen Sulfide SCHEMBL7496567 | 0.76 | GSK3B (0.95) | GSK3BPTPN1KMT2ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973936-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998046786-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |